Plakophilin 4 antibody (AA 185-234)

Catalog No. ABIN1451430

The Rabbit Polyclonal anti-Plakophilin 4 antibody (ABIN1451430) specifically detects Plakophilin 4 in WB, IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for Plakophilin 4 antibody (AA 185-234) (ABIN1451430)

Target: Plakophilin 4 (PKP4)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plakophilin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Plakophilin 4 Antibody

Binding Specificity: AA 185-234

Purpose: Plakophilin 4 Antibody

Specificity: Plakophilin 4 Polyclonal Antibody detects endogenous levels of Plakophilin 4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PKP4. AA range:185-234

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Plakophilin 4

Target: Plakophilin 4 (PKP4)

Alternative Name: PKP4

Background:

Synonyms: PKP4; Plakophilin-4; p0071

Background: Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015],

Gene Name: PKP4

Protein Name: Plakophilin-4

Molecular Weight: 134 kDa

Gene ID: 604276

UniProt: Q99569

Pathways: Cell-Cell Junction Organization