DDX20 antibody (AA 273-322)

Catalog No. ABIN1451457

The Rabbit Polyclonal anti-DDX20 antibody (ABIN1451457) specifically detects DDX20 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for DDX20 antibody (AA 273-322) (ABIN1451457)

Target: DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX20 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DDX20 Antibody

Binding Specificity: AA 273-322

Purpose: Gemin3 Antibody

Specificity: Gemin3 Polyclonal Antibody detects endogenous levels of Gemin3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human DDX20. AA range:273-322

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DDX20

Target: DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))

Alternative Name: DDX20

Background:

Synonyms: DDX20, DP103, GEMIN3, Probable ATP-dependent RNA helicase DDX20, Component of gems 3, DEAD box protein 20, DEAD box protein DP 103, Gemin-3

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008],

Gene Name: DDX20

Protein Name: Probable ATP-dependent RNA helicase DDX20

Molecular Weight: 92 kDa

Gene ID: 11218

OMIM: 606168

UniProt: Q9UHI6

Pathways: Ribonucleoprotein Complex Subunit Organization