SERGEF antibody (AA 179-228)

Catalog No. ABIN1451589

The Rabbit Polyclonal anti-SERGEF antibody (ABIN1451589) specifically detects SERGEF in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SERGEF antibody (AA 179-228) (ABIN1451589)

Target: SERGEF (Secretion Regulating Guanine Nucleotide Exchange Factor (SERGEF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERGEF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SERGEF Antibody

Binding Specificity: AA 179-228

Purpose: SERGEF Antibody

Specificity: SERGEF Polyclonal Antibody detects endogenous levels of SERGEF protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SERGEF

Target: SERGEF (Secretion Regulating Guanine Nucleotide Exchange Factor (SERGEF))

Alternative Name: SERGEF

Background:

Synonyms: SERGEF, DELGEF, GNEFR, Secretion-regulating guanine nucleotide exchange factor, Deafness locus-associated putative guanine nucleotide exchange factor, DelGEF, Guanine nucleotide exchange factor-related protein

Background: function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,

Gene Name: SERGEF

Protein Name: Secretion-regulating guanine nucleotide exchange factor

Molecular Weight: 48 kDa

Gene ID: 26297

OMIM: 606051

UniProt: Q9UGK8