TBX3 antibody (AA 271-320)

Catalog No. ABIN1451829

The Rabbit Polyclonal anti-TBX3 antibody (ABIN1451829) specifically detects TBX3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TBX3 antibody (AA 271-320) (ABIN1451829)

Target: TBX3 (T-Box 3 (TBX3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TBX3 Antibody

Binding Specificity: AA 271-320

Purpose: TBX2/3 Antibody

Specificity: TBX2/3 Polyclonal Antibody detects endogenous levels of TBX2/3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human TBX3. AA range:271-320

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TBX3

Target: TBX3 (T-Box 3 (TBX3))

Alternative Name: TBX3

Background:

Synonyms: TBX3, T-box transcription factor TBX3, T-box protein 3, TBX2, T-box transcription factor TBX2, T-box protein 2

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: TBX2/TBX3

Protein Name: T-box transcription factor TBX2/3

Molecular Weight: 79 kDa

Gene ID: 6926

OMIM: 181450

UniProt: O15119

Pathways: Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development