SRCIN1 antibody (AA 811-860)

Catalog No. ABIN1451982

The Rabbit Polyclonal anti-SRCIN1 antibody (ABIN1451982) specifically detects SRCIN1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SRCIN1 antibody (AA 811-860) (ABIN1451982)

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRCIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SRCIN1 Antibody

Binding Specificity: AA 811-860

Purpose: p140Cap Antibody

Specificity: P140Cap Polyclonal Antibody detects endogenous levels of p140Cap protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human SNIP. AA range:811-860

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SRCIN1

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Alternative Name: SNIP

Background:

Synonyms: SRCIN1, KIAA1684, P140, SRC kinase signaling inhibitor 1, SNAP-25-interacting protein, SNIP, p130Cas-associated protein, p140Cap

Background: function:Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells.,PTM:Tyrosine-phosphorylated in response to EGF and to cell adhesion to integrin ligands.,similarity:Belongs to the p140Cap family.,subcellular location:Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions.,subunit:Interacts with the N-terminal coiled-coil region of SNAP25 (By similarity). Interacts with BCAR1/p130Cas through its C-terminal domain.,

Gene Name: SRCIN1

Protein Name: SRC kinase signaling inhibitor 1

Molecular Weight: 112 kDa

Gene ID: 80725

OMIM: 610786

UniProt: Q9C0H9