TRAF4 antibody (AA 261-310)

Catalog No. ABIN1451997

The Rabbit Polyclonal anti-TRAF4 antibody (ABIN1451997) specifically detects TRAF4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TRAF4 antibody (AA 261-310) (ABIN1451997)

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRAF4 Antibody

Binding Specificity: AA 261-310

Purpose: TRAF4 Antibody

Specificity: TRAF4 Polyclonal Antibody detects endogenous levels of TRAF4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human TRAF4. AA range:261-310

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Alternative Name: TRAF4

Background:

Synonyms: TRAF4, CART1, MLN62, RNF83, TNF receptor-associated factor 4, Cysteine-rich domain associated with RING and Traf domains protein 1, Metastatic lymph node gene 62 protein, MLN 62, RING finger protein 83

Background: TNF receptor associated factor 4(TRAF4) Homo sapiens This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008],

Gene Name: TRAF4

Protein Name: TNF receptor-associated factor 4

Molecular Weight: 53 kDa

Gene ID: 9618

OMIM: 602464

UniProt: Q9BUZ4