NRF1 antibody (AA 221-270)

Catalog No. ABIN1452021

The Rabbit Polyclonal anti-NRF1 antibody (ABIN1452021) specifically detects NRF1 in WB and ELISA. The antibody is reactive with Human, Mouse, Rat and Cow samples.

Quick Overview for NRF1 antibody (AA 221-270) (ABIN1452021)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NRF1 Antibody

Binding Specificity: AA 221-270

Purpose: NRF-1 Antibody

Specificity: NRF-1 Polyclonal Antibody detects endogenous levels of NRF-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NRF1. AA range:221-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Alternative Name: NRF1

Background:

Synonyms: NRF1; Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal

Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014],

Gene Name: NRF1

Protein Name: Nuclear respiratory factor 1

Molecular Weight: 53 kDa

Gene ID: 4899

OMIM: 600879

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha