ITIH4 antibody (Cleaved-Arg661)

Catalog No. ABIN1452240

The Rabbit Polyclonal anti-ITIH4 antibody (ABIN1452240) specifically detects ITIH4 in IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for ITIH4 antibody (Cleaved-Arg661) (ABIN1452240)

Target: ITIH4 (Inter alpha Globulin Inhibitor H4 (ITIH4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITIH4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ITIH4 Antibody

Binding Specificity: AA 612-661, Cleaved-Arg661

Purpose: Cleaved-ITI-H4 70k (R661) Antibody

Specificity: Cleaved-ITI-H4 70k (R661) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H4 70k protein resulting from cleavage adjacent to R661.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ITIH4. AA range:612-661

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ITIH4

Target: ITIH4 (Inter alpha Globulin Inhibitor H4 (ITIH4))

Alternative Name: ITIH4

Background:

Synonyms: ITIH4, IHRP, ITIHL1, PK120, Inter-alpha-trypsin inhibitor heavy chain H4, ITI heavy chain H4, ITI-HC4, Inter-alpha-inhibitor heavy chain 4, Inter-alpha-trypsin inhibitor family heavy chain-related protein, IHRP, Plasma kallikrein sensitive

Background: The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

Gene Name: ITIH4

Protein Name: Inter-alpha-trypsin inhibitor heavy chain H4

Molecular Weight: 103 kDa

Gene ID: 3700

OMIM: 600564

UniProt: Q14624

Pathways: Glycosaminoglycan Metabolic Process