MMP10 antibody (Cleaved-Phe99)

Catalog No. ABIN1452258

The Rabbit Polyclonal anti-MMP10 antibody (ABIN1452258) specifically detects MMP10 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MMP10 antibody (Cleaved-Phe99) (ABIN1452258)

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MMP10 Antibody

Binding Specificity: AA 80-129, Cleaved-Phe99

Purpose: Cleaved-MMP-10 (F99) Antibody

Specificity: Cleaved-MMP-10 (F99) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-10 protein resulting from cleavage adjacent to F99.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MMP10. AA range:80-129

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MMP10

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Alternative Name: MMP10

Background:

Synonyms: MMP10, STMY2, Stromelysin-2, SL-2, Matrix metalloproteinase-10, MMP-10, Transin-2

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],

Gene Name: MMP10

Protein Name: Stromelysin-2

Molecular Weight: 54 kDa

Gene ID: 4319

OMIM: 185260

UniProt: P09238