PLG antibody (Cleaved-Val98)

Catalog No. ABIN1452261

The Rabbit Polyclonal anti-PLG antibody (ABIN1452261) specifically detects PLG in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLG antibody (Cleaved-Val98) (ABIN1452261)

Target: PLG (Plasminogen (PLG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLG Antibody

Binding Specificity: AA 79-128, Cleaved-Val98

Purpose: Cleaved-Plasminogen HC A short form (V98) Antibody

Specificity: Cleaved-Plasminogen HC A short form (V98) Polyclonal Antibody detects endogenous levels of fragment of activated Plasminogen HC A short form protein resulting from cleavage adjacent to V98.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PLMN. AA range:79-128

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PLG

Target: PLG (Plasminogen (PLG))

Background:

Synonyms: PLG, Plasminogen

Background: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009],

Gene Name: PLG

Protein Name: Plasminogen

Molecular Weight: 90 kDa

Gene ID: 5340

OMIM: 173350

UniProt: P00747

Pathways: Complement System, Lipid Metabolism