Cathepsin G antibody (AA 67-116)

Catalog No. ABIN1453038

The Rabbit Polyclonal anti-Cathepsin G antibody is suitable to detect Cathepsin G in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Cathepsin G antibody (AA 67-116) (ABIN1453038)

Target: Cathepsin G (CTSG)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin G antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cathepsin G Antibody

Binding Specificity: AA 67-116

Purpose: Cathepsin G Antibody

Specificity: Cathepsin G Polyclonal Antibody detects endogenous levels of Cathepsin G protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Cathepsin G. AA range:67-116

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cathepsin G

Target: Cathepsin G (CTSG)

Alternative Name: Cathepsin G

Background:

Synonyms: CTSG, Cathepsin G, CG

Background: The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014],

Gene Name: CTSG

Protein Name: Cathepsin G

Molecular Weight: 28 kDa

Gene ID: 1511

OMIM: 116830

UniProt: P08311

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones