IGLL1 antibody (AA 26-75)

Catalog No. ABIN1453056

The Rabbit Polyclonal anti-IGLL1 antibody (ABIN1453056) specifically detects IGLL1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IGLL1 antibody (AA 26-75) (ABIN1453056)

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGLL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IGLL1 Antibody

Binding Specificity: AA 26-75

Purpose: CD179b Antibody

Specificity: CD179b Polyclonal Antibody detects endogenous levels of CD179b protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human CD179b. AA range:26-75

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IGLL1

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Alternative Name: CD179b

Background:

Synonyms: IGLL1, IGL1, Immunoglobulin lambda-like polypeptide 1, CD179 antigen-like family member B, Ig lambda-5, Immunoglobulin omega polypeptide, Immunoglobulin-related protein 14.1, CD antigen CD179b, IGLC1, Ig lambda-1 chain C regions, IGLC2, Ig

Background: immunoglobulin lambda like polypeptide 1(IGLL1) Homo sapiens The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain.This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: IGLL1/IGLC1/IGLC2/IGLC3/IGLC6/IGLC7

Protein Name: Immunoglobulin lambda-like polypeptide 1

Molecular Weight: 22 kDa

Gene ID: 3543

OMIM: 146770

UniProt: P15814

Pathways: Regulation of Cell Size