COX10 antibody (AA 98-147)

Catalog No. ABIN1453164

The Rabbit Polyclonal anti-COX10 antibody (ABIN1453164) specifically detects COX10 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for COX10 antibody (AA 98-147) (ABIN1453164)

Target: COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-COX10 Antibody

Binding Specificity: AA 98-147

Purpose: COX10 Antibody

Specificity: COX10 Polyclonal Antibody detects endogenous levels of COX10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human COX10. AA range:98-147

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for COX10

Target: COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

Alternative Name: COX10

Background:

Synonyms: COX10, Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lys

Gene Name: COX10

Protein Name: Protoheme IX farnesyltransferase mitochondrial

Molecular Weight: 48 kDa

Gene ID: 1352

OMIM: 602125

UniProt: Q12887