EOMES antibody (AA 59-108)

Catalog No. ABIN1453260

The Rabbit Polyclonal anti-EOMES antibody (ABIN1453260) specifically detects EOMES in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for EOMES antibody (AA 59-108) (ABIN1453260)

Target: EOMES (Eomesodermin (EOMES))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EOMES antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EOMES Antibody

Binding Specificity: AA 59-108

Purpose: EOMES Antibody

Specificity: EOMES Polyclonal Antibody detects endogenous levels of EOMES protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EOMES

Target: EOMES (Eomesodermin (EOMES))

Alternative Name: EOMES

Background:

Synonyms: EOMES, TBR2, Eomesodermin homolog, T-box brain protein 2, T-brain-2, TBR-2

Background: This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Gene Name: EOMES

Protein Name: Eomesodermin homolog

Molecular Weight: 72 kDa

Gene ID: 8320

OMIM: 604615

UniProt: O95936

Pathways: Stem Cell Maintenance