FASTK antibody (AA 361-410)

Catalog No. ABIN1453275

The Rabbit Polyclonal anti-FASTK antibody (ABIN1453275) specifically detects FASTK in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FASTK antibody (AA 361-410) (ABIN1453275)

Target: FASTK (Fas-Activated serine/threonine Kinase (FASTK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FASTK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FASTK Antibody

Binding Specificity: AA 361-410

Purpose: FAST Antibody

Specificity: FAST Polyclonal Antibody detects endogenous levels of FAST protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human FAST. AA range:361-410

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FASTK

Target: FASTK (Fas-Activated serine/threonine Kinase (FASTK))

Alternative Name: FAST

Background:

Synonyms: FASTK, Fas-activated serine/threonine kinase, FAST kinase

Background: The protein encoded byThis gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008],

Gene Name: FASTK

Protein Name: Fas-activated serine/threonine kinase

Molecular Weight: 61 kDa

Gene ID: 10922

OMIM: 606965

UniProt: Q14296