GUCY1A1 antibody (AA 374-423)

Catalog No. ABIN1453332

The Rabbit Polyclonal anti-GUCY1A1 antibody (ABIN1453332) specifically detects GUCY1A1 in WB, ELISA, IHC, IF and Co-IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GUCY1A1 antibody (AA 374-423) (ABIN1453332)

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Co-Immunoprecipitation ( Co-IP)

Product Details anti-GUCY1A1 Antibody

Binding Specificity: AA 374-423

Purpose: GCS-α-1 Antibody

Specificity: GCS-α-1 Polyclonal Antibody detects endogenous levels of GCS-α-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human GCS-alpha-1. AA range:374-423

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GUCY1A1

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Alternative Name: GCS-Alpha-1

Background:

Synonyms: GUCY1A3; GUC1A3; GUCSA3; GUCY1A1; Guanylate cyclase soluble subunit alpha-3; GCS-alpha-3; GCS-alpha-1; Soluble guanylate cyclase large subunit

Background: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate.The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Gene Name: GUCY1A3

Protein Name: Guanylate cyclase soluble subunit alpha-3

Molecular Weight: 77 kDa

Gene ID: 2982

OMIM: 139396

UniProt: Q02108

Pathways: Myometrial Relaxation and Contraction