RPSA/Laminin Receptor antibody (AA 166-215)
Quick Overview for RPSA/Laminin Receptor antibody (AA 166-215) (ABIN1453533)
Target
See all RPSA/Laminin Receptor (RPSA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 166-215
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Purpose
- Laminin-R Antibody
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Specificity
- Laminin-R Polyclonal Antibody detects endogenous levels of Laminin-R protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Laminin-R. AA range:166-215
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Isotype
- IgG
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Application Notes
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
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Alternative Name
- Laminin-R
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Background
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Synonyms: RPSA, LAMBR, LAMR1, 40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Colon carcinoma laminin-binding protein, Laminin receptor 1, LamR, Laminin-binding pr
Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins.This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in
Gene Name: RPSA
Protein Name: 40S ribosomal protein SA
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Molecular Weight
- 32 kDa
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Gene ID
- 3921
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OMIM
- 150370
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UniProt
- P08865
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Target
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