BIRC7 antibody (AA 162-211)

Catalog No. ABIN1453581

The Rabbit Polyclonal anti-BIRC7 antibody (ABIN1453581) specifically detects BIRC7 in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BIRC7 antibody (AA 162-211) (ABIN1453581)

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BIRC7 Antibody

Binding Specificity: AA 162-211

Purpose: ML-IAP Antibody

Specificity: ML-IAP Polyclonal Antibody detects endogenous levels of ML-IAP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ML-IAP. AA range:162-211

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Alternative Name: ML-IAP

Background:

Synonyms: BIRC7, KIAP, LIVIN, MLIAP, RNF50, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, KIAP, Livin, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein 50

Background: This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013],

Gene Name: BIRC7

Protein Name: Baculoviral IAP repeat-containing protein 7

Molecular Weight: 32 kDa

Gene ID: 79444

OMIM: 605737

UniProt: Q96CA5