MYD88 antibody (AA 171-220)

Catalog No. ABIN1453590

This anti-MYD88 antibody is a Rabbit Polyclonal antibody detecting MYD88 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 1 publication.

Quick Overview for MYD88 antibody (AA 171-220) (ABIN1453590)

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYD88 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-MYD88 Antibody

Binding Specificity: AA 171-220

Specificity:

MyD88 antibody detects endogenous levels of MyD88.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MyD88.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

References for anti-MYD88 antibody (ABIN1453590)

Valerio, Minderman, Mace, Awad: "β-Sitosterol modulates TLR4 receptor expression and intracellular MyD88-dependent pathway activation in J774A.1 murine macrophages." in: Cellular immunology, Vol. 285, Issue 1-2, pp. 76-83, (2014) (PubMed).

Target Details for MYD88

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Alternative Name: MyD88

Background:

Synonyms: Myeloid differentiation primary response protein MyD88, MYD88

NCBI Gene Symbol: MyD88

Molecular Weight: 33 kDa

Gene ID: 4615

OMIM: 602170

UniProt: Q99836

Pathways: NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades