NEFL antibody (AA 295-344)

Catalog No. ABIN1453644

The Rabbit Polyclonal anti-NEFL antibody (ABIN1453644) specifically detects NEFL in WB, ELISA, IHC (p) and IF (p). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for NEFL antibody (AA 295-344) (ABIN1453644)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NEFL Antibody

Binding Specificity: AA 295-344

Purpose: NF-L Antibody

Specificity: NF-L Polyclonal Antibody detects endogenous levels of NF-L protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NF-L. AA range:295-344

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Alternative Name: NF-L

Background:

Synonyms: NEFL, NF68, NFL, Neurofilament light polypeptide, NF-L, 68 kDa neurofilament protein, Neurofilament triplet L protein

Background: nuclear factor of activated T-cells 5(NFAT5) Homo sapiens The product ofThis gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: NEFL

Protein Name: Neurofilament light polypeptide

Molecular Weight: 61 kDa

OMIM: 162280

UniProt: P07196