NPY antibody (AA 45-94)

Catalog No. ABIN1453677

The Rabbit Polyclonal anti-NPY antibody (ABIN1453677) specifically detects NPY in WB, IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for NPY antibody (AA 45-94) (ABIN1453677)

Target: NPY (Neuropeptide Y (NPY))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-NPY Antibody

Binding Specificity: AA 45-94

Purpose: NPY Antibody

Specificity: NPY Polyclonal Antibody detects endogenous levels of NPY protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NPY. AA range:45-94

Isotype: IgG

Application Details

Application Notes: IHC 1:100-500,WB 1:500-2000,ELISA 1:5000-20000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NPY

Target: NPY (Neuropeptide Y (NPY))

Alternative Name: NPY

Background:

Synonyms: NPY, Pro-neuropeptide Y

Background: This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014],

Gene Name: NPY

Protein Name: Pro-neuropeptide Y

Molecular Weight: 10 kDa

Gene ID: 4852

OMIM: 162640

UniProt: P01303

Pathways: Feeding Behaviour