OPCML antibody (AA 152-201)

Catalog No. ABIN1453695

The Rabbit Polyclonal anti-OPCML antibody (ABIN1453695) specifically detects OPCML in WB and ELISA. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for OPCML antibody (AA 152-201) (ABIN1453695)

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPCML antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OPCML Antibody

Binding Specificity: AA 152-201

Purpose: OBCAM Antibody

Specificity: OBCAM Polyclonal Antibody detects endogenous levels of OBCAM protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human OBCAM. AA range:152-201

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for OPCML

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Alternative Name: OBCAM

Background:

Synonyms: OPCML, IGLON1, OBCAM, Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule, IgLON family member 1

Background: This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],

Gene Name: OPCML

Protein Name: Opioid-binding protein/cell adhesion molecule

Molecular Weight: 38 kDa

Gene ID: 4978

OMIM: 600632

UniProt: Q14982