OCRL antibody (AA 150-199)

Catalog No. ABIN1453701

The Rabbit Polyclonal anti-OCRL antibody (ABIN1453701) specifically detects OCRL in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for OCRL antibody (AA 150-199) (ABIN1453701)

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OCRL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OCRL Antibody

Binding Specificity: AA 150-199

Purpose: OCRL Antibody

Specificity: OCRL Polyclonal Antibody detects endogenous levels of OCRL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human OCRL. AA range:150-199

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Alternative Name: OCRL

Background:

Synonyms: OCRL, INPP5F, OCRL1, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein

Background: This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

Gene Name: OCRL

Protein Name: Inositol polyphosphate 5-phosphatase OCRL-1

Molecular Weight: 104 kDa

Gene ID: 4952

OMIM: 300535

UniProt: Q01968

Pathways: Inositol Metabolic Process