Urotensin 2 antibody (AA 48-97)

Catalog No. ABIN1454067

The Rabbit Polyclonal anti-Urotensin 2 antibody (ABIN1454067) specifically detects Urotensin 2 in WB and ELISA. The antibody is reactive with Human and Monkey samples.

Quick Overview for Urotensin 2 antibody (AA 48-97) (ABIN1454067)

Target: Urotensin 2 (UTS2)

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Urotensin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Urotensin 2 Antibody

Binding Specificity: AA 48-97

Purpose: Urotensin II Antibody

Specificity: Urotensin II Polyclonal Antibody detects endogenous levels of Urotensin II protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Urotensin II. AA range:48-97

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Urotensin 2

Target: Urotensin 2 (UTS2)

Alternative Name: Urotensin II

Background:

Synonyms: UTS2, Urotensin-2, Urotensin II, U-II, UII

Background: This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Gene Name: UTS2

Protein Name: Urotensin-2

Molecular Weight: 14 kDa

Gene ID: 10911

OMIM: 604097

UniProt: O95399

Pathways: Negative Regulation of Hormone Secretion