TJP2 antibody (AA 1063-1112)

Catalog No. ABIN1454106

The Rabbit Polyclonal anti-TJP2 antibody (ABIN1454106) specifically detects TJP2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TJP2 antibody (AA 1063-1112) (ABIN1454106)

Target: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TJP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TJP2 Antibody

Binding Specificity: AA 1063-1112

Purpose: ZO-2 Antibody

Specificity: ZO-2 Polyclonal Antibody detects endogenous levels of ZO-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human ZO-2. AA range:1063-1112

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TJP2

Target: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Alternative Name: ZO-2

Background:

Synonyms: TJP2, X104, ZO2, Tight junction protein ZO-2, Tight junction protein 2, Zona occludens protein 2, Zonula occludens protein 2

Background: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Gene Name: TJP2

Protein Name: Tight junction protein ZO-2

Molecular Weight: 133 kDa

Gene ID: 9414

OMIM: 607709

UniProt: Q9UDY2