PTK2B antibody (AA 812-861)

Catalog No. ABIN1500493

This Rabbit Polyclonal antibody specifically detects PTK2B in WB, IHC and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Pig, Horse, Monkey, Cow, Guinea Pig and Bat.

Quick Overview for PTK2B antibody (AA 812-861) (ABIN1500493)

Target: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Pig, Horse, Monkey, Cow, Guinea Pig, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTK2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PTK2B Antibody

Binding Specificity: AA 812-861

Brand: IHC-plus™

Specificity: Human PTK2B / PYK2

Purification: Protein A purified

Immunogen: Synthetic peptide located between aa812-861 of human PTK2B (Q14289, NP_004094). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig (100%), Galago, Elephant, Opossum (92%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 - 5 μg/mL), WB (1.25 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for PTK2B

Target: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Alternative Name: PTK2B / PYK2

Background: Name/Gene ID: PTK2B
Subfamily: Focal Adhesion Kinase
Family: Protein Kinase

Synonyms: PTK2B, CADTK, CAKB, Cell adhesion kinase beta, FADK 2, FADK2, Focal adhesion kinase 2, FRNK, FAK2, Proline-rich tyrosine kinase 2, Protein-tyrosine kinase 2-beta, Protein kinase B, Protein tyrosine kinase 2 beta, PYK2, RAFTK, CAK-beta, PKB, PTK

Gene ID: 2185

NCBI Accession: NP_004094

UniProt: Q14289

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling