RCC1 antibody

Catalog No. ABIN1512845

The Rabbit Monoclonal anti-RCC1 antibody is suitable to detect RCC1 in samples from Human. It has been validated for WB and IHC.

Quick Overview for RCC1 antibody (ABIN1512845)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RCC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RCC1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human RCC1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Alternative Name: RCC1

Background: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA.,CHC1, RCC1-I, SNHG3-RCC1,Cell Biology & Developmental Biology,Cell Cycle,RCC1

Molecular Weight: 45 kDa

Gene ID: 1104

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus