RCC1 antibody

Catalog No. ABIN6242601

The Mouse Monoclonal anti-RCC1 antibody is suitable to detect RCC1 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for RCC1 antibody (ABIN6242601)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This RCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 332CT2-1-1

Product Details anti-RCC1 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This RCC1 monoclonal antibody is generated from mouse immunized with RCC1 recombinant protein.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:100~250. WB: 1:2000-1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Alternative Name: RCC1

Background: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Molecular Weight: 44969

NCBI Accession: NP_001041659, NP_001041660, NP_001041664, NP_001260

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus