MTHFR antibody (AA 1-230)

Catalog No. ABIN1513224

The Rabbit Polyclonal anti-MTHFR antibody (ABIN1513224) specifically detects MTHFR in WB. The antibody is reactive with Human samples.

Quick Overview for MTHFR antibody (AA 1-230) (ABIN1513224)

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTHFR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTHFR Antibody

Binding Specificity: AA 1-230

Sequence: MVNEARGNSS LNPCLEGSAS SGSESSKDSS RCSTPGLDPE RHERLREKMR RRLESGDKWF SLEFFPPRTA EGAVNLISRF DRMAAGGPLY IDVTWHPAGD PGSDKETSSM MIASTAVNYC GLETILHMTC CRQRLEEITG HLHKAKQLGL KNIMALRGDP IGDQWEEEEG GFNYAVDLVK HIRSEFGDYF DICVAGYPKG HPEAGSFEAD LKHLKEKVSA GADFIITQLF

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MTHFR (NP_005948.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MTHFR

Target: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Alternative Name: MTHFR

Background: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.,MTHFR,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,MTHFR

Molecular Weight: 75 kDa

Gene ID: 4524

UniProt: P42898

Pathways: Methionine Biosynthetic Process