MYOC antibody (AA 245-504)

Catalog No. ABIN3022197

The Rabbit Polyclonal anti-MYOC antibody has been validated for WB. It is suitable to detect MYOC in samples from Human.

Quick Overview for MYOC antibody (AA 245-504) (ABIN3022197)

Target: MYOC (Myocilin (MYOC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYOC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYOC Antibody

Binding Specificity: AA 245-504

Sequence: CGELVWVGEP LTLRTAETIT GKYGVWMRDP KPTYPYTQET TWRIDTVGTD VRQVFEYDLI SQFMQGYPSK VHILPRPLES TGAVVYSGSL YFQGAESRTV IRYELNTETV KAEKEIPGAG YHGQFPYSWG GYTDIDLAVD EAGLWVIYST DEAKGAIVLS KLNPENLELE QTWETNIRKQ SVANAFIICG TLYTVSSYTS ADATVNFAYD TGTGISKTLT IPFKNRYKYS SMIDYNPLEK KLFAWDNLNM VTYDIKLSKM

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 245-504 of human MYOC (NP_000252.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MYOC

Target: MYOC (Myocilin (MYOC))

Alternative Name: MYOC

Background: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.,MYOC,GLC1A,GPOA,JOAG,JOAG1,TIGR,myocilin,Epigenetics & Nuclear Signaling,Neuroscience,MYOC

Molecular Weight: 56 kDa

Gene ID: 4653

UniProt: Q99972