MYOC antibody

Catalog No. ABIN7229868

The Rabbit Polyclonal anti-MYOC antibody is suitable to detect MYOC in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for MYOC antibody (ABIN7229868)

Target: MYOC (Myocilin (MYOC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYOC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MYOC Antibody

Purpose: Rabbit Anti-MYOC Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MYOC protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MYOC protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MYOC

Target: MYOC (Myocilin (MYOC))

Alternative Name: MYOC

Background: Myocilin, Myocilin 55 kDa subunit, Trabecular meshwork-induced glucocorticoid response proteinMYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Molecular Weight: 55kD

Gene ID: 4653

UniProt: Q99972