TRKB antibody (pTyr706)

Catalog No. ABIN1531204

The Rabbit Polyclonal anti-TRKB antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect TRKB in samples from Human, Rat and Mouse.

Quick Overview for TRKB antibody (pTyr706) (ABIN1531204)

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRKB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-TRKB Antibody

Binding Specificity: AA 671-720, pTyr706

Specificity:

Trk B (Phospho-Tyr705) Antibody detects endogenous levels of Trk B only when phosphorylated at Tyr705.

PhosphorylationH:Y706 M:Y705 R:Y705

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Trk B around the phosphorylation site of Tyr705.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000

Comment:

Unigene-Number: Hs.494312, Hs.712776 (NCBI Gene Symbol: NTRK2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for TRKB

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Alternative Name: Trk B

Background:

Synonyms: BDNF/NT-3 growth factors receptor precursor, GP145-TrkB, GP145-TrkB/GP95-TrkB, NTRK2, Trk-B, TrkB tyrosine kinase, kinase TrkB

NCBI Gene Symbol: NTRK2

Molecular Weight: 91 kDa

Gene ID: 4915

OMIM: 600456

UniProt: Q16620

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport