FANCD2 antibody (pSer222)

Catalog No. ABIN1531273

The Rabbit Polyclonal anti-FANCD2 antibody has been validated for WB, IHC and ELISA. It is suitable to detect FANCD2 in samples from Human, Mouse and Rat.

Quick Overview for FANCD2 antibody (pSer222) (ABIN1531273)

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-FANCD2 Antibody

Binding Specificity: AA 188-237, pSer222

Specificity:

FANCD2 (Phospho-Ser222) Antibody detects endogenous levels of FANCD2 only when phosphorylated at Ser222.

PhosphorylationH:S222 M:S220 R:S222

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FANCD2 around the phosphorylation site of Ser222.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.208388 (NCBI Gene Symbol: FANCD2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for FANCD2

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Alternative Name: FANCD2

Background:

Synonyms: FACD2, FANCD2, Fanconi anemia complementation group D2 protein

NCBI Gene Symbol: FANCD2

Molecular Weight: 166 kDa

Gene ID: 2177

OMIM: 227646

UniProt: Q9BXW9

Pathways: DNA Damage Repair