Glycogen Synthase antibody (pSer645)

Catalog No. ABIN1531276

The Rabbit Polyclonal anti-Glycogen Synthase antibody is suitable to detect Glycogen Synthase in samples from Human, Mouse and Rat. It has been validated for WB, IF, IHC and ELISA.

Quick Overview for Glycogen Synthase antibody (pSer645) (ABIN1531276)

Target: Glycogen Synthase (GYS)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Product Details anti-Glycogen Synthase Antibody

Binding Specificity: AA 611-660, pSer645

Purpose: Glycogen Synthase 1 (phospho Ser645) Antibody

Specificity: Phospho-Glycogen Synthase 1 (S645) Polyclonal Antibody detects endogenous levels of Glycogen Synthase 1 protein only when phosphorylated at S645.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Glycogen Synthase around the phosphorylation site of Ser645. AA range:611-660

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Glycogen Synthase

Target: Glycogen Synthase (GYS)

Alternative Name: Glycogen Synthase

Background:

Synonyms: GYS1, GYS, Glycogen [starch] synthase, muscle

Background: The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],

Gene Name: GYS1

Protein Name: Glycogen [starch] synthase muscle

Molecular Weight: 83 kDa

Gene ID: 2997

OMIM: 138570

UniProt: P13807