PRAS40 antibody (pThr246)

Catalog No. ABIN1531296

This Rabbit Polyclonal antibody specifically detects PRAS40 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PRAS40 antibody (pThr246) (ABIN1531296)

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRAS40 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRAS40 Antibody

Binding Specificity: AA 207-256, pThr246

Specificity:

Akt1 S1 (Phospho-Thr246) Antibody detects endogenous levels of Akt1 S1 only when phosphorylated at Thr246.

PhosphorylationH:T246 M:T247 R:T262

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Akt1 S1 around the phosphorylation site of Thr246.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:10000

Comment:

Unigene-Number: Hs.515542 (NCBI Gene Symbol: AKT1S1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PRAS40

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Alternative Name: Akt1 S1

Background:

Synonyms: Akt1 substrate 1 (proline-rich), AKTS1, Lobe, MGC2865, PRAS40, proline-rich Akt substrate 40 kDa

NCBI Gene Symbol: AKT1S1

Molecular Weight: 27 kDa

Gene ID: 84335

OMIM: 610221

UniProt: Q96B36

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect