DCLRE1C antibody (pSer516)

Catalog No. ABIN1531298

The Rabbit Polyclonal anti-DCLRE1C antibody (ABIN1531298) specifically detects DCLRE1C in WB, ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for DCLRE1C antibody (pSer516) (ABIN1531298)

Target: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCLRE1C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DCLRE1C Antibody

Binding Specificity: AA 482-531, pSer516

Specificity:

Artemis (Phospho-Ser516) Antibody detects endogenous levels of Artemis only when phosphorylated at Ser516.

PhosphorylationH:S516 M:S518

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Artemis around the phosphorylation site of Ser516.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.656065 (NCBI Gene Symbol: DCLRE1C)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for DCLRE1C

Target: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Alternative Name: Artemis

Background:

Synonyms: A-SCID protein, ARTEMIS, ASCID, DCLRE1C, DCR1C, DNA cross-link repair 1C protein, SCIDA, SNM1- like protein, SNM1C

NCBI Gene Symbol: DCLRE1C

Molecular Weight: 78 kDa

Gene ID: 64421

OMIM: 602450

UniProt: Q96SD1

Pathways: DNA Damage Repair