Ret Proto-Oncogene antibody (pTyr1015)

Catalog No. ABIN1531387

The Rabbit Polyclonal anti-Ret Proto-Oncogene antibody has been validated for WB and ELISA. It is suitable to detect Ret Proto-Oncogene in samples from Human, Mouse and Rat.

Quick Overview for Ret Proto-Oncogene antibody (pTyr1015) (ABIN1531387)

Target: Ret Proto-Oncogene (RET)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ret Proto-Oncogene antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Ret Proto-Oncogene Antibody

Binding Specificity: AA 991-1040, pTyr1015

Specificity:

Ret (Phospho-Tyr1015) Antibody detects endogenous levels of Ret only when phosphorylated at Tyr1015.

PhosphorylationH:Y1015 M:Y1016 R:Y1017

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Ret around the phosphorylation site of Tyr1015.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:1000

Comment:

Unigene-Number: Hs.350321 (NCBI Gene Symbol: RET)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Alternative Name: Ret

Background:

Synonyms: C-ret, kinase Ret, Proto-oncogene ret precursor

NCBI Gene Symbol: RET

Molecular Weight: 124 kDa

Gene ID: 5979

OMIM: 114500

UniProt: P07949

Pathways: RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation