BMX antibody (pTyr40)

Catalog No. ABIN1531433

The Rabbit Polyclonal anti-BMX antibody is suitable to detect BMX in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for BMX antibody (pTyr40) (ABIN1531433)

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-BMX Antibody

Binding Specificity: AA 6-55, pTyr40

Purpose: Bmx (phospho Tyr40) Antibody

Specificity: Phospho-Bmx (Y40) Polyclonal Antibody detects endogenous levels of Bmx protein only when phosphorylated at Y40.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ETK around the phosphorylation site of Tyr40. AA range:6-55

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BMX

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Alternative Name: ETK

Background:

Synonyms: BMX, Cytoplasmic tyrosine-protein kinase BMX, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase, ETK, NTK38

Background: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],

Gene Name: BMX

Protein Name: Cytoplasmic tyrosine-protein kinase BMX

Molecular Weight: 78 kDa

Gene ID: 660

OMIM: 300101

UniProt: P51813