BCL2L1 antibody (pThr47)

Catalog No. ABIN1531492

Product Details anti-BCL2L1 Antibody

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Binding Specificity: AA 13-62, pThr47

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Specificity:

BCL-XL (Phospho-Thr47) Antibody detects endogenous levels of BCL-XL only when phosphorylated at Thr47.

PhosphorylationH:T47 M:T47 R:T47

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BCL-XL around the phosphorylation site of Thr47.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:40000

Comment:

Unigene-Number: Hs.516966 (NCBI Gene Symbol: BCL2L1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Alternative Name: BCL-XL (BCL2L1 Products)

Background:

Synonyms: Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L, BCL2L1, BCLX, BCLXL, BLC2L

NCBI Gene Symbol: BCL2L1

Molecular Weight: 26 kDa

Gene ID: 598

OMIM: 600039

UniProt: Q07817

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling