HDAC1 antibody (pSer421)

Catalog No. ABIN1531502

The Rabbit Polyclonal anti-HDAC1 antibody is suitable to detect HDAC1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for HDAC1 antibody (pSer421) (ABIN1531502)

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HDAC1 Antibody

Binding Specificity: AA 387-436, pSer421

Specificity:

HDAC1 (Phospho-Ser421) Antibody detects endogenous levels of HDAC1 only when phosphorylated at Ser421.

PhosphorylationH:S421 M:S421 R:S421

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HDAC1 around the phosphorylation site of Ser421.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:5000

Comment:

Unigene-Number: Hs.88556 (NCBI Gene Symbol: HDAC1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for HDAC1

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Alternative Name: HDAC1

Background:

Synonyms: HD1, Histone deacetylase 1, RPD3L1

NCBI Gene Symbol: HDAC1

Molecular Weight: 55 kDa

Gene ID: 3065

OMIM: 601241

UniProt: Q13547

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis