CASR antibody (pThr888)

Catalog No. ABIN1531528

This Rabbit Polyclonal antibody specifically detects CASR in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CASR antibody (pThr888) (ABIN1531528)

Target: CASR (Calcium-Sensing Receptor (CASR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CASR Antibody

Binding Specificity: AA 854-903, pThr888

Specificity:

Calcium Sensing Receptor (Phospho-Thr888) Antibody detects endogenous levels of Calcium Sensing Receptor only when phosphorylated at Thr888.

PhosphorylationH:T888 M:T888 R:T888

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor around the phosphorylation site of Thr888.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:40000

Comment:

Unigene-Number: Hs.435615 (NCBI Gene Symbol: CASR)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CASR

Target: CASR (Calcium-Sensing Receptor (CASR))

Alternative Name: Calcium Sensing Receptor

Background:

Synonyms: Extracellular calcium-sensing receptor, CaSR, Parathyroid Cell calcium-sensing receptor, PCaR1, CASR, GPRC2A, PCAR1

NCBI Gene Symbol: CASR

Molecular Weight: 120 kDa

Gene ID: 846

OMIM: 145980

UniProt: P41180

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis