Calmodulin 1 antibody (pSer81, pThr79)

Catalog No. ABIN1531529

There is 1 publication for this product available. The Rabbit Polyclonal anti-Calmodulin 1 antibody is suitable to detect Calmodulin 1 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for Calmodulin 1 antibody (pSer81, pThr79) (ABIN1531529)

Target: Calmodulin 1 (CALM1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calmodulin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Calmodulin 1 Antibody

Binding Specificity: AA 46-95, pSer81, pThr79

Purpose: Calmodulin-1 (phospho Thr80/S82) Antibody

Specificity: Phospho-Calmodulin (T80/S82) Polyclonal Antibody detects endogenous levels of Calmodulin protein only when phosphorylated at T80/S82.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Calmodulin-1 around the phosphorylation site of Thr79 and Ser81. AA range:46-95

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

References for anti-Calmodulin 1 antibody (ABIN1531529)

Yokokura, Yurimoto, Matsuoka, Imataki, Dobashi, Bandoh, Matsunaga: "Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma." in: BMC cancer, Vol. 14, pp. 882, (2014) (PubMed).

Target Details for Calmodulin 1

Target: Calmodulin 1 (CALM1)

Alternative Name: Calmodulin

Background:

Synonyms: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII, Calmodulin, CaM

Background: This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],

Gene Name: CALM1

Protein Name: Calmodulin-1

Molecular Weight: 16 kDa

Gene ID: 801, 805, 808

OMIM: 114180

UniProt: P0DP23

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling