C5AR1 antibody (pSer338)

Catalog No. ABIN1531549

This Rabbit Polyclonal antibody specifically detects C5AR1 in ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for C5AR1 antibody (pSer338) (ABIN1531549)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C5AR1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-C5AR1 Antibody

Binding Specificity: AA 301-350, pSer338

Purpose: CD88 (phospho Ser338) Antibody

Specificity: Phospho-CD88 (S338) Polyclonal Antibody detects endogenous levels of CD88 protein only when phosphorylated at S338.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CD88/C5aR around the phosphorylation site of Ser338. AA range:301-350

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Alternative Name: CD88/C5aR

Background:

Synonyms: C5AR1, C5AR, C5R1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, CD antigen CD88

Background: function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Gene Name: C5AR1

Protein Name: C5a anaphylatoxin chemotactic receptor

Molecular Weight: 39 kDa

Gene ID: 728

OMIM: 113995

UniProt: P21730

Pathways: Complement System