GATA3 antibody (pSer308)

Catalog No. ABIN1531601

The Rabbit Polyclonal anti-GATA3 antibody is suitable to detect GATA3 in samples from Human and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for GATA3 antibody (pSer308) (ABIN1531601)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-GATA3 Antibody

Binding Specificity: AA 274-323, pSer308

Purpose: GATA-3 (phospho Ser308) Antibody

Specificity: Phospho-GATA-3 (S308) Polyclonal Antibody detects endogenous levels of GATA-3 protein only when phosphorylated at S308.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GATA3 around the phosphorylation site of Ser308. AA range:274-323

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Alternative Name: GATA3

Background:

Synonyms: GATA3, Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3

Background: This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009],

Gene Name: GATA3

Protein Name: Trans-acting T-cell-specific transcription factor GATA-3

Molecular Weight: 47 kDa

Gene ID: 2625

OMIM: 131320

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation