HCK antibody (pTyr410)

Catalog No. ABIN1531606

This Rabbit Polyclonal antibody specifically detects HCK in ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HCK antibody (pTyr410) (ABIN1531606)

Target: HCK (Hemopoietic Cell Kinase (HCK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCK antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-HCK Antibody

Binding Specificity: AA 381-430, pTyr410

Specificity:

HCK (Phospho-Tyr410) Antibody detects endogenous levels of HCK only when phosphorylated at Tyr410.

PhosphorylationH:Y410 M:Y408 R:Y409

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HCK around the phosphorylation site of Tyr410.

Isotype: IgG

Application Details

Application Notes: IF: 1:100~1:500 ELISA: 1:20000

Comment:

Unigene-Number: Hs.655210 (NCBI Gene Symbol: HCK)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for HCK

Target: HCK (Hemopoietic Cell Kinase (HCK))

Alternative Name: HCK

Background:

Synonyms: B-cell/myeloid kinase, BMK, Hemopoietic cell kinase, kinase Hck, P56-HCK and P60-HCK, p59-HCK/p60-HCK, Tyrosine-protein kinase HCK

NCBI Gene Symbol: HCK

Molecular Weight: 59 kDa

Gene ID: 3055

OMIM: 142370

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling