ERBB3 antibody (pTyr1289)

Catalog No. ABIN1531610

The Rabbit Polyclonal anti-ERBB3 antibody has been validated for ELISA and IF. It is suitable to detect ERBB3 in samples from Human, Mouse and Rat.

Quick Overview for ERBB3 antibody (pTyr1289) (ABIN1531610)

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-ERBB3 Antibody

Binding Specificity: AA 1256-1305, pTyr1289

Specificity:

HER3 (Phospho-Tyr1289) Antibody detects endogenous levels of HER3 only when phosphorylated at Tyr1289.

PhosphorylationH:Y1289 M:Y1286 R:Y1286

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HER3 around the phosphorylation site of Tyr1289.

Isotype: IgG

Application Details

Application Notes: IF: 1:100~1:500 ELISA: 1:10000

Comment:

Unigene-Number: Hs.118681 (NCBI Gene Symbol: ERBB3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ERBB3

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Alternative Name: HER3

Background:

Synonyms: c-erbB3, ERB3, ERBB3, HER3, kinase ErbB3, Receptor protein-tyrosine kinase erbB-3 precursor, Tyrosine kinase-type cell surface receptor HER3

NCBI Gene Symbol: ERBB3

Molecular Weight: 148 kDa

Gene ID: 2065

OMIM: 190151

UniProt: P21860

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway