Tryptophan Hydroxylase 1 antibody (pSer58)

Catalog No. ABIN1531637

The Rabbit Polyclonal anti-Tryptophan Hydroxylase 1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect Tryptophan Hydroxylase 1 in samples from Human, Mouse and Rat.

Quick Overview for Tryptophan Hydroxylase 1 antibody (pSer58) (ABIN1531637)

Target: Tryptophan Hydroxylase 1 (TPH1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Tryptophan Hydroxylase 1 Antibody

Binding Specificity: AA 26-75, pSer58

Specificity:

Tryptophan Hydroxylase (Phospho-Ser58) Antibody detects endogenous levels of Tryptophan Hydroxylase only when phosphorylated at Ser58.

PhosphorylationH:S58 M:S61 R:S58

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Tryptophan Hydroxylase around the phosphorylation site of Ser58.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.591999 (NCBI Gene Symbol: TPH1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Tryptophan Hydroxylase 1

Target: Tryptophan Hydroxylase 1 (TPH1)

Alternative Name: Tryptophan Hydroxylase

Background:

Synonyms: TPH, TRPH, tryptophan 5-hydroxylase 1, tryptophan 5-monooxygenase 1

NCBI Gene Symbol: TPH1

Molecular Weight: 50 kDa

Gene ID: 7166

OMIM: 191060

UniProt: P17752

Pathways: Feeding Behaviour