Tryptophan Hydroxylase 1 antibody (AA 345-444)

Catalog No. ABIN3022155

This Rabbit Polyclonal antibody specifically detects Tryptophan Hydroxylase 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Tryptophan Hydroxylase 1 antibody (AA 345-444) (ABIN3022155)

Target: Tryptophan Hydroxylase 1 (TPH1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tryptophan Hydroxylase 1 Antibody

Binding Specificity: AA 345-444

Sequence: LSGHAKVKPF DPKITCKQEC LITTFQDVYF VSESFEDAKE KMREFTKTIK RPFGVKYNPY TRSIQILKDT KSITSAMNEL QHDLDVVSDA LAKVSRKPSI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 345-444 of human TPH1 (NP_004170.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Tryptophan Hydroxylase 1

Target: Tryptophan Hydroxylase 1 (TPH1)

Alternative Name: TPH1

Background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.,TPH1,TPRH,TRPH,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,TPH1

Molecular Weight: 50 kDa/53 kDa

Gene ID: 7166

UniProt: P17752

Pathways: Feeding Behaviour