HRS (HRS) (AA 301-350), (pTyr334) antibody

Catalog No. ABIN1531658

The Rabbit Polyclonal anti-HRS antibody is suitable to detect HRS in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for HRS (HRS) (AA 301-350), (pTyr334) antibody (ABIN1531658)

Target: HRS

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 301-350, pTyr334

Specificity:

HRS (Phospho-Tyr334) Antibody detects endogenous levels of HRS only when phosphorylated at Tyr334.

PhosphorylationH:Y334 M:Y334 R:Y334

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HRS around the phosphorylation site of Tyr334.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.514590 (NCBI Gene Symbol: HGS)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details

Target: HRS

Alternative Name: HRS

Background:

Synonyms: Hepatocyte growth factor-regulated tyrosine kinase substrate, HGS, IMOS-1

NCBI Gene Symbol: HGS

Molecular Weight: 86 kDa

Gene ID: 9146

OMIM: 604375

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation