HRS (HRS) (AA 301-350), (pTyr334) antibody

Catalog No. ABIN1531658

The Rabbit Polyclonal anti- antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect in samples from Human, Mouse and Rat.

Quick Overview for HRS (HRS) (AA 301-350), (pTyr334) antibody (ABIN1531658)

Target: HRS

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 301-350, pTyr334

Specificity:

HRS (Phospho-Tyr334) Antibody detects endogenous levels of HRS only when phosphorylated at Tyr334.

PhosphorylationH:Y334 M:Y334 R:Y334

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HRS around the phosphorylation site of Tyr334.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.514590 (NCBI Gene Symbol: HGS)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details

Target: HRS

Alternative Name: HRS

Background:

Synonyms: Hepatocyte growth factor-regulated tyrosine kinase substrate, HGS, IMOS-1

NCBI Gene Symbol: HGS

Molecular Weight: 86 kDa

Gene ID: 9146

OMIM: 604375

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation