IL4 Receptor antibody (pTyr497)

Catalog No. ABIN1531667

Product Details anti-IL4 Receptor Antibody

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Binding Specificity: AA 463-512, pTyr497

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL4 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity:

IL-4R/CD124 (Phospho-Tyr497) Antibody detects endogenous levels of IL-4R/CD124 only when phosphorylated at Tyr497.

PhosphorylationH:Y497 M:Y500

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IL-4R/CD124 around the phosphorylation site of Tyr497.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.513457 (NCBI Gene Symbol: IL4R)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for IL4 Receptor

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Alternative Name: IL-4R/CD124 (IL4R Products)

Background:

Synonyms: 582J2.1, CD124 antigen, IL-4R-alpha, IL4RA, Interleukin-4 receptor alpha chain precursor

NCBI Gene Symbol: IL4R

Molecular Weight: 89 kDa

Gene ID: 3566

OMIM: 147781

UniProt: P24394

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process