IL4 Receptor antibody (pTyr497)

Catalog No. ABIN1531667

The Rabbit Polyclonal anti-IL4 Receptor antibody is suitable to detect IL4 Receptor in samples from Human and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for IL4 Receptor antibody (pTyr497) (ABIN1531667)

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL4 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-IL4 Receptor Antibody

Binding Specificity: AA 463-512, pTyr497

Specificity:

IL-4R/CD124 (Phospho-Tyr497) Antibody detects endogenous levels of IL-4R/CD124 only when phosphorylated at Tyr497.

PhosphorylationH:Y497 M:Y500

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IL-4R/CD124 around the phosphorylation site of Tyr497.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.513457 (NCBI Gene Symbol: IL4R)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for IL4 Receptor

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Alternative Name: IL-4R/CD124

Background:

Synonyms: 582J2.1, CD124 antigen, IL-4R-alpha, IL4RA, Interleukin-4 receptor alpha chain precursor

NCBI Gene Symbol: IL4R

Molecular Weight: 89 kDa

Gene ID: 3566

OMIM: 147781

UniProt: P24394

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process